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kinase domain
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doc. Mgr. Kateřina Machová Poláková Ph.D.
Academic staff at First Faculty of Medicine
13 publications
Publications
publication
Somatic Mutations in Oncogenes Are in Chronic Myeloid Leukemia Acquired De Novo via Deregulated Base-Excision Repair and Alternative Non-Homologous End Joining
2021 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Physical Education and Sport
publication
Sensitivity and reliability of DNA-based mutation analysis by allele-specific digital PCR to follow resistant BCR-ABL1-positive cells
2021 |
First Faculty of Medicine
publication
Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target
2016 |
First Faculty of Medicine, Faculty of Science
publication
Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase
2015 |
First Faculty of Medicine
publication
Exosomes released by imatinib-resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib-sensitive cells in the presence of imatinib
2021 |
First Faculty of Medicine, Faculty of Science, Central Library of Charles University
publication
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission
2020 |
First Faculty of Medicine, Second Faculty of Medicine
publication
BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia.
2018 |
First Faculty of Medicine, Central Library of Charles University
publication
BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia
2018 |
First Faculty of Medicine, Central Library of Charles University
publication
Genotypes of SLC22A4 and SLC22A5 regulatory loci are predictive of the response of chronic myeloid leukemia patients to imatinib treatment
2017 |
First Faculty of Medicine, Faculty of Science, Faculty of Medicine in Hradec Králové
publication
Interferon-alpha Revisited: Individualized Treatment Management Eased the Selective Pressure of Tyrosine Kinase Inhibitors on BCR-ABL1 Mutations Resulting in a Molecular Response in High-Risk CML Patients
2016 |
First Faculty of Medicine, Faculty of Science, Third Faculty of Medicine
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