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synthesizing
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RNDr. Jana Janočková Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
37 publications
Publications
publication
Discovery of Dual A beta/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease
2022 |
Publication without faculty affiliation
publication
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
2021 |
Publication without faculty affiliation
publication
N-alkylated tacrine derivatives as potential agents in Alzheimer's disease therapy
2019 |
Faculty of Medicine in Hradec Králové
publication
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy
2019 |
Publication without faculty affiliation
publication
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers
2019 |
Publication without faculty affiliation
publication
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
2019 |
Publication without faculty affiliation
publication
Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro
2018 |
Publication without faculty affiliation
publication
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation
2017 |
Publication without faculty affiliation
publication
Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment
2017 |
Publication without faculty affiliation
publication
Novel Tacrine-Scutellarin hybrids as multipotent Anti-Alzheimer's agents: Design, synthesis and biological evaluation
2017 |
Publication without faculty affiliation
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