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Multi-target directed ligand
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RNDr. Jana Janočková Ph.D.
Externí akademický pracovník na Lékařská fakulta v Hradci Králové
37 publikací
Publikace
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Farmaceutická fakulta v Hradci Králové, 1. lékařská fakulta
publication
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease
2021 |
Publikace bez příslušnosti k fakultě
publication
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
2020 |
Publikace bez příslušnosti k fakultě
publication
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
2019 |
Publikace bez příslušnosti k fakultě
publication
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
2019 |
Publikace bez příslušnosti k fakultě
publication
Profiling donepezil template into multipotent hybrids with antioxidant properties
2018 |
Publikace bez příslušnosti k fakultě
publication
Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment
2017 |
Publikace bez příslušnosti k fakultě
publication
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
2022 |
Lékařská fakulta v Hradci Králové
publication
Discovery of Dual A beta/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease
2022 |
Publikace bez příslušnosti k fakultě
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Lékařská fakulta v Hradci Králové, Ústřední knihovna
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