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DNA ADDUCTS
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Person
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prof. MUDr. Tomáš Eckschlager CSc.
Academic staff at Second Faculty of Medicine
330 publications
Publications
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Faculty of Science, Second Faculty of Medicine
publication
Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Catalytic Electrochemical Analysis of Platinum in Pt-DNA Adducts
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the P-32-postlabeling technique
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Ellipticine cytotoxicity to cancer cell lines - a comparative study
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
2007 |
Faculty of Science, Second Faculty of Medicine, Central Library of Charles University
publication
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells
2007 |
Faculty of Science, Second Faculty of Medicine
publication
Premature aging in childhood cancer survivors (Review)
2023 |
Second Faculty of Medicine
publication
KDM5B expression in cisplatin resistant neuroblastoma cell lines
2022 |
Second Faculty of Medicine
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