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Non-covalent binding
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prof. MUDr. Tomáš Eckschlager CSc.
Academic staff at Second Faculty of Medicine
330 publications
Publications
publication
Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the P-32-postlabeling technique
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
2007 |
Faculty of Science, Second Faculty of Medicine, Central Library of Charles University
publication
Premature aging in childhood cancer survivors (Review)
2023 |
Second Faculty of Medicine
publication
KDM5B expression in cisplatin resistant neuroblastoma cell lines
2022 |
Second Faculty of Medicine
publication
Semen analysis and treatment risk factors in long-term survivors of childhood cancer
2021 |
Second Faculty of Medicine, Central Library of Charles University
publication
Nanomedicine of tyrosine kinase inhibitors
2021 |
Faculty of Science, Second Faculty of Medicine
publication
Apoferritin/vandetanib association is long-term stable but does not improve pharmacological properties of vandetanib
2021 |
Faculty of Science, Second Faculty of Medicine
publication
Is There a Higher Incidence of Sporadic Renal Angiomyolipoma in Childhood Cancer Survivors?
2021 |
Second Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
2021 |
Second Faculty of Medicine
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