Publications
- Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters2019 | Faculty of Pharmacy in Hradec Králové
- Phenolic N-monosubstituted carbamates: Antitubercular and toxicity evaluation of multi-targeting compounds2019 | Faculty of Pharmacy in Hradec Králové
- Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment2018 | Faculty of Pharmacy in Hradec Králové
- Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C32014 | Faculty of Pharmacy in Hradec Králové
- Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)benzoates2013 | Faculty of Pharmacy in Hradec Králové
- Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase2012 | Faculty of Pharmacy in Hradec Králové
- Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter2022 | Faculty of Pharmacy in Hradec Králové
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