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ENZYME
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Person
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prof. RNDr. Jiří Hudeček CSc.
Academic staff at Faculty of Science
3 classes
123 publications
Classes
class
Hemeproteins and metalloproteins
MC250P11 |
Faculty of Science
class
Structure of biopolymers
MC250P10 |
Faculty of Science
class
Life - Molecules and Biochemistry
MC250P70 |
Faculty of Science
Publications
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Flexibility of human cytochrome P450 enzymes: Molecular dynamics and spectroscopy reveal important function-related variations
2011 |
Faculty of Science
publication
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases
2011 |
Faculty of Science
publication
Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: Possible role of Arg 133 in modulation of function and activity of this enzyme
2008 |
Faculty of Science
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid
2008 |
Faculty of Science
publication
Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 ? similarity between human and rat enzymes
2008 |
Faculty of Science
publication
Contribution of Biotransformation Enzymes to the Development of Renal Injury and Urothelial Cancer Caused by Aristolochic Acid: Urgent Questions, Difficult Answers
2008 |
Faculty of Science
publication
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
+1
2008 |
Faculty of Science
publication
Structural analysis of cytochromes P450 shows differences in flexibility of heme 2-and 4-vinyls
2007 |
Faculty of Science
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