Publication at Faculty of Medicine in Hradec Králové |
2010
Abstract
Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review or preclinical EGG.
Our group recently set up and worked out the methods for EGG in experimental pigs. We gained our initial experience in the use of EGG in assessment of porcine gastric myoelectric activity after volume change and after intragastric administration of itopride and erythromycin.
The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible.
Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology.