Cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems

Abstract

The paper describes novel unique data showing that cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems.

Keywords

• cytochrome P450 3A
• α-naphthoflavone
• testosterone
• metabolism
• cooperativity
• enzymatic oxidation