Identification of human enzymes oxidizing a human metabolite of carcinogenic 2-nitroanisole, 2-nitrophenol. Evidence for its oxidative detoxification by human cytochromes P450.

Abstract

The paper describes identification of human enzymes oxidizing a human metabolite of carcinogenic 2-nitroanisole, 2-nitrophenol. It is also evidence for its oxidative detoxification by human cytochromes P450.

Keywords

• 2-nitrophenol
• 2-nitroanisole
• cytochrome P450
• oxidation
• detoxification