Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans

Abstract

The paper describes rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans.

Keywords

• o-anisidine
• N-(2-Methoxyphenyl)hydroxylamine
• o-aminophenol
• metabolism
• activation
• detoxification