Abstract
Bevacizumab (Avastin) is a humanized monoclonal antibody to vascular endothelial growth factor A that is approved for the treatment of metastatic colorectal cancer. Although this drug is off-label for intaocular use, it has been widely used as intravitreal therapy for lot of ocular diseases.
This paper will describe the efficacy and safety of the intraocular Avastin in the treatment of ocular diseases. The results described in the article warrant further study of bevacizumab in larger, controlled, randomized trials.