Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o- nitroanisole

Abstract

In the paper, identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl) hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole was described.

Keywords

• rat
• cytochrome
• P450
• N-(2-methoxyphenyl)hydroxylamine
• environmental pollutants
• carcinogens
• o-anisidine
• nitroanisole