Iliac vein thrombosis: feasibility assessment of randomized controlled trials of endovascular pharmacomechanical thrombolysis
2010
Abstract
All patients with incident leg deep vein thrombosis during the calendar year 2005 seen at the Mayo Clinic were identified to determine the frequency of iliac vein involvement and the number undergoing endovascular therapies. Ninety-five (of 394) patients had iliac vein involvement.
Of these, only nine patients would have been suitable for randomization. The number of cases that could potentially be randomized into a clinical trial is relatively small.
Trial design may require either multicenter cooperation or exclusion criteria revision for adequate recruitment.