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Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate centributors to cell death during the late phase of viral infection

Publication at Faculty of Science |
2010

Abstract

Mouse polyomavirus minor capsid proteins were found to be a very potent inducers of apoptosis dependent on caspase activation. Immuno-electron microscopy showed the minor proteins, VP2 and VP3, to be asociated with damaged membranes of the endoplasmic reticulum, nuclear envelope and mitochondria.