The prediction of achievement of chronic viral hepatitis C therapy response by use of ROC analysis.

Abstract

Our work analyzes the group of 93 patients with chronic hepatitis C under treatment, with the view of the possibility to determine the predictive factors. Using the statistical data processing, especially ROC analysis, we tried to define the predictive factors.

According to our findings we conclude that the crucial for SVR prediction is the monitoring of HCV viremia level 7 days and 3 months after the introduction of antiviral therapy, the monitoring of ALT activity, especially ALT/AST ratio prior to therapy introduction and after 4 weeks.

Keywords

• chronic hepatits C
• the prediction of the therapy success
• ROC
• SVR