Salicylanilide carbamates: Antitubercular agents active against multidrug-resistant Mycobacterium tuberculosis strains

Abstract

A series of 27 salicylanilide-based carbamates was prepared as a part of our ongoing search for new antituberculosis drugs. These compounds exhibited very good antimycobacterial activity against M. tuberculosis as well as MDR strains.

Keywords

• salicylanilide carbamates
• multidrug-resistant tuberculosis
• in vitro antimycobacterial activity
• cytotoxicity
• chemical hydrolysis