Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity

Abstract

This experimental in vitro study evaluated various iron chelators that are used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity.

Keywords

• Catecholamine cardiotoxicity
• Iron chelation
• Desferrioxamine (DFO)
• Deferiprone (L1)
• Deferasirox (ICL670A)