Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures

Abstrakt

In the paper, we describe expression and ontogeny of AHR/Ahr and ARNT/Arnt and systematically characterize induction of major AHR target genes in human placental trophoblast forming the placental maternal-fetal morphological and metabolic barrier.

Klíčová slova

• aryl hydrocarbon receptor
• aryl hydrocarbon receptor nuclear translocator
• CYP1A1
• cytochrome P450
• placenta
• trophoblast