This study evaluated the predictive value of serum biomarkers for liver hypertrophy and tumor progression after PVE. The significant predictive biomarkers of PVE inclued serum TPA levels, monototal, IGF-BP3, IGF1, TGF- alfa, EGF, HGF,VEGF, TNF alfa and IL-10 before PVE; and TK, TPA, monototal, IGF-BP3, TGF alfa and IL-8 over the course of 28 days after PVE.