Multiple (familial) trichoepitheliomas: a clinicopathological and molecular biological study, including CYLD and PTCH gene analysis, of a series of 16 patients

Abstract

Multiple familial trichoepitheliomas (MFT) constitute an autosomally inherited syndrome possibly related to Brooke-Spiegler syndrome (BSS). A clinicopathological and molecular biological study.

Keywords

• multiple familial trichoepitheliomas
• Brooke-Spiegler syndrome
• CYLD gene
• PTCH gene
• basal cell carcinoma
• cylindromatosis
• cutaneous adnexal neoplasms
• melanocytic hyperplasia