Primary signet-ring cell//histiocytoid carcinoma of the eyelid: A clinicopathologic study of 5 cases and review of the literature

Abstract

Primary cutaneous signet-ring cell carcinomas are rare and aggressive neoplasms. These neoplasms have been mostly described in the eyelids, and more uncommonly, in the axillary skin.

Keywords

• signet-ring cells
• histiocytoid cells
• eyelid carcinoma
• metastatic lobular breast carcinoma
• immunohistochemistry
• p63
• EGFR
• MUC-1
• MUC-2
• mammaglobin
• E-cadherin