Prevalence of Human Leukocyte Antigen (HLA)-B*5701 in HIV-infected Subjects in Czech Republic

Abstract

The HLA-B*57:01 allele is associated with a hypersensitivity reaction to abacavir, and its prevalence varies in different populations. The aim of the study was to investigate HLA-B*57:01 prevalence in the Czech HIV-infected population.

HLA-B*57:01 prevalence in our cohort was 5.33%, which is similar to the situation in other Central European countries.

Keywords

• abacavir
• hypersensitivity
• HLA-B*57:01
• prevalence
• Czech Republic