Morphometric analysis of the porcine gastrointestinal tract in a 10-day high-dose indomethacin administration with or without probiotic bacteria Escherichia coli Nissle 1917

Abstract

Indomethacin alone induced marked adaptation of the gastric mucosa. Escherichia coli Nissle alone provided a significant favourable trophic effect on the colonic mucosa.

However, indomethacin and probiotics administered together comprise the worst impact on all porcine stomach, small and large bowel.

Keywords

• morphometric analysis
• porcine gastrointestinal tract
• indomethacin
• probiotics
• Escherichia coli Nissle 1917