Publication at Faculty of Medicine in Hradec Králové |
2011
Abstract
Chronic lymphocytic leukemia (CLL) is the most common leukemia type in Western countries. Even incidence of CLL is high, this disease remained beyond interest for a very long time.
However, in the last few years of this disease fundamentally changed and due to intensive study, new knowledge especially on pathogenesis, prognostic factors and therapy based on intensive therapeutic procedures were made. Today we know that usage of classical prognostic factors is insufficient for prognosis evaluation in the individuals.
However modern and new markers have potential to distinguish patients in early stages to groups with significantly different prognosis and predict clinical course of the disease.