Malignant lymphomas of non-Hodgkin type in the annals in Department of Dentistry in Hradec Králové 1998-2008
Abstract
Malignant lymphomas of non-Hodgkin type (NHL) are the second most frequent malignant tumors in the head and neck area. The retrospective study included 24 patients diagnosed for NHL.
The follow up study concerned 22 individuals, while 13 of them had been treated by chemotherapy, 7 by immunotherapy, one by a combination of radio- and chemotherapy, and one by surgery. In 7 cases there was a nodal affection, in 17 cases extranodal NHL of salivary glands, alveolar ridge, buccal and vestibular mucosa, cheek, palate and tongue.
On the whole, 91.7 % of the NHL were of B-cell origin. In the group of nodal lymphomas, the follicular lymphoma was most frequent (6 cases), in the extranodal tumor group, the follicular lymphoma was also most frequent (6 cases), followed by diffuse large cell B lymphoma (4 cases) and extranodal lymphoma from marginal zone (2 cases).
Early and rapid diagnosis of NHL in the area of the head and neck can principally influence the prognosis of the disease.