The problems of proteinuria measurement in urine with presence of Bence Jones protein

Abstrakt

Protein concentration measurement in the urine can be problematic in the presence of Bence Jones protein. We have carried out an external quality control assessment with the participation of 79 clinical biochemistry laboratories from the Czech Republic and Slovakia.

Our results highlight the challenges of reliable and reproducible measurement of urinary protein in the presence of Bence Jones protein.

Klíčová slova

• Bence Jones protein
• proteinuria
• electrophoresis
• free light chains
• monoclonal gammopathies