Modern and conventional prognostic markers of chronic lymphocytic leukaemia in the everyday haematological practice
2011
Abstract
The impact of modern prognostic markers on clinical course of chronic lymphocytic leukaemia (CLL) in everyday practice has been not yet well defined, especially in large series of patients. Therefore, the goal of this study was to assess the influence of conventional as well as modern prognostic factors on overall survival and time to therapy of patients with CLL.
The total of 1300 patients was included in the analysis. Based on our results, the examination of biological prognostic markers can give an insight into the possible disease evolution in daily clinical practice.
Biological prognostic mrkers are, however, not ready to be used for guidance of therapy at least outside of clinical trials.