Publikace na Přírodovědecká fakulta |
2011
Abstrakt
Proteins of glutamatergic NMDA receptor signaling pathways have been studied as targets for intervention in a variety of neuropathological conditions, including neurodegenerations, epilepsy, neuropathic pain, drug addiction, and schizophrenia. High activity NMDA-blocking agents have been designed to treat some of these disorders; however, their effect is often compromised by undesirable side effects.
Therefore, alternative ways of modulating NMDA receptor function need to be sought after.