Abstract
Infective endocarditis (IE) is a severe disease. It is known, that some underlying cardiac conditions are associated with the risk of acquisition of IE.
Transient bacteremia is commonly associated with some medical procedures. Antibiotic prophylaxis has been recommended before them although valid data supporting this practise does not exist.
Vice versa bacteremia is much more frequently associated with routine daily activities (tooth brushing, chewing food, flossing). Accordingly, recently published foreign guidelines recommend to reduce prophylactic antibiotics use.
Administration of antibiotic prophylaxis is now recommended only fo patients with underlying cardiac conditions associated with the highest risk of adverse outcome from IE.