Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial

Abstrakt

New agents that are active in patients with metastatic colorectal cancer are needed. Patupilone (EPO906, epothilone B) is a novel microtubulestabilising agent.

Klíčová slova

• patupilone
• dose escalation
• epothilone B
• metastatic colon cancer
• microtubule stabiliser