Time-Dependent Oxidation during Nano-Assisted Laser Desorption Ionization Mass Spectrometry: A Useful Tool for Structure Determination or a Source of Possible Confusion?

Abstrakt

A new and extremely simple approach for determination of a double bond position by a laser desorption ionization mass spectrometry. It is solely based on the catalytic properties of nanostructured surfaces used in nanoassisted laser desorption ionization experiments.

These surfaces can induce oxidation of analytes, which results in a mass shift that can be detected by mass spectrometry. The ability to determine a position of a double bond was demonstrated on polyunsaturated phospholipids and cyclosporine A

Klíčová slova

• double-bond position
• unsaturated fatty-acids
• electrospray-ionization
• silicon nanowires
• desorption/ionization
• elucidation
• ozonolysis
• target
• matrix
• lipids