Publikace na Přírodovědecká fakulta |
2011
Abstrakt
Hydrogen/Deuterium exchange coupled to mass spectrometry is routinely used to study protein folding and interactions. Major drawback of this technique is the laborious data mining and lack of software tools facilitating this step and allowing easy data interpretation and visualization.
Here we present freely accessible set of tools useful in preparation of HXMS experiment as well as in presentation of HXMS data. Simple PHP scripts aid e.g. in drawing of deuteration plots, protection plots, heat map representations, colorization of protein models, peptide maps