Publication at First Faculty of Medicine, Faculty of Medicine in Pilsen |
2011
Abstract
In the view of increasing bacterial resistance is the lack of antimicrobials with new type of action against G-negative multiresistant pathogens essential problem. The situation in G-positive infections is more favorable.
New molecules of antibiotics are synthesized in groups of glycylcyclins, cyclic lipopeptides, oxazolidines, cephalosporins and semisynthetic glycopeptides. On the contrary the perspective of treatment of resistant G-negative infections in intensive care is unfavorable, because the new effective antibiotics will not be available earlier than in 10 years.