Increased platelet residual activity in patients treated with acetosalicylic acid is associated with increased tissue factor and decreased tissue factor pathway inhibitor plasma levels
2011
Abstract
There are several reasons for an anadequate suppression of platelet aggreagation ranging from a patient's non-compliance, inadequate dosage of the drug, poor absorption from gastrointestinal tract, and interaction with other drugs to genetic polymorphisms. An important role may also play the interaction with other factors including tissue factor (TF)and tissue factor pathway inhibitor (TFPI)...