Preparation of synthetic HA scaffold and the effect of heat treatment on bone formation

Abstract

The process of precipitation and coagulation can be applied to obtain pure synthetic HA powder.Foaming with H2O2 represents a method suitable to produce HA scaffold with higher surface area and porosity. The physico-chemical properties of HA granules and in vivo tests determined that synthetic scaffold is comparable with bovine bone material.

No significant differences between synthetic HA150 scaffolds and bovine bone BioOss were observed in vivo. The heat treatment of HA results in slower resorption and remodeling.