Publication at Faculty of Medicine in Hradec Králové |
2009
Abstract
Crohn's disease is an inflammatory process and is associated with several metabolic disturbances and recent clinical studies have established a link between lipid metabolism and systemic inflammation. Serum concentrations of total cholesterol, LDL- and HDL-cholesterol and non-cholesterol sterols were evaluated in 24 patients with active Crohn's disease during a period of 28 days.
The lower serum levels of total cholesterol (P<0,001), LDL- and HDL-cholesterol (P<0,05) together with significantly lower plasma levels of lathosterol (P<0,001) and campesterol (P<0,001) in the patients with active Crohn's disease than in the control group were detected