Wiskott-Aldrich syndrome - Disease Requiring Early Transplantation of Hemopoietic Stem Cells

Abstract

The problem of necessary correct and early establishment of diagnosis is documented on case histories of 6 patients handed over to our workplace and indicated to allogenic transplantation of hemopoietic stem cells (SCT) in the years 1996-2007. SCT is presently the only possibility to cure up WAS and the successfulness is markedly dependent on early establishment of diagnosis and efficient prophylaxis and directed therapy of infectious complications.

Keywords

• Wiskott-Aldrich syndrome
• WASP gene
• thrombocytopenia
• eczema
• primary immunodeficiency
• transplantation of hemopoietic stem cells