Cytostatic tetrazole-butenolide conjugates: linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances

Abstract

The results of in vitro testing and study of structure-activity of cytostatic tetrazole-butenolide conjugates showed a promising activity against both leukemic cells HL-60 and CCRF-CEM, and pathogenic fungi, particularly in ethylsulfanyl derivative.