Publication
Abstract
The aims were; firstly, to ivestigate the applicability of lithium microdialysis for monitoring blood flow changes due to ischemia/reperfusion in rat stomach and colon submucosa and to assess the systemic effects on selected enzymes and nitric oxide; secondly, to evaluate local impact of caffeine on gastric submucosal microcirculation, nitric oxide release and its systemic effect on oxidative stress-related marker malondialdehyde; and finally, to develop a microdialysis method of continuous mucosal permeability measurement in rat descending colon