Monitoring of anti-tumour cell-mediated response in patients with renal carcinoma, disturbance of T cell proliferation
2008
Abstract
The mentioned results prove that the characteristics and intesity of anti-tumour responses are different in compared compartments (tumour/PBL). CD3+/CD8+ T lymphocytes are the dominant lymphocytic population of TILs.
The knowledge of phenotype and functions of effector cells, which are responsible for anti-tumour response, are the basic precondition for understanding the anti-tumour immune response and the cause of its failure.