: Potential uses of assessment of functional changes in primary hemostasis by the PFA-100 analyser and modified assessment of platelet aggregation in rationalizing management of patients with familiar hypercholesterolemia treated by extracorporeal LDL-cholesterol elimination
2007
Abstract
In patients with familiar hypercholesterolemia, LDL-apheresis results in primary hemostasis normalization. Modified assessment of platelet aggregation might become another suitable tool for monitoring the activity of the process in these severely-ill patients.
While being relatively more available, judging by initial experience, separate examination using the PFA-100 analyzer seems unsuitable for current assessment of the optimal intensity of individual LDL-apheresis procedures.