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Essential PTX3 biology (not only) for cardiologists and cardiac surgeons

Publication at Faculty of Medicine in Hradec Králové |
2007

Abstract

Inflammation has been recognized to form an integral part of the atherosclerotic process. Much consideration has been given lately to the role played in atherogenesis by C-reactive protein (CRP). Although not accepted unequivocally, CRP appears to be not only a maker, but also an active mediator of the arherosclerotic process.

Pentraxin 3 (PTX3) is a newly identified acute phase reactant which shares some structural and some functional properties with CRP.