Rationalization of therapeutic LDL-apheresis procedure with analysis of primary hemostasis application of PFA-100 analysis and modified platelets aggregation

Abstract

LDL-apheresis is a therapeutic method used for treating patients with severe hyperlipidemia, it improves hemostasis too. Changes of primary haemostasis detected with PFA-100 analyzer seems to be not significant in our study (p<0,14).

However, modified platelets aggregation seems to be more suitable marker to determine the optimal intensity of individual LDL-apheresis with statistically significantly improved results (p<0.05).

Keywords

• hemostasis
• platelets aggregation
• PFA-100
• LDL-apheresis
• atherosclerosis