Publication at Faculty of Medicine in Hradec Králové |
2005
Abstract
41 patients with psoriasis were treated with 7,5 mg or 15 mg MTX administered once a week. The pharmacokinetic of MTX were evaluated at week 1 and 13, MTX in erythrocytes and the PASI-score were evaluated repeatedly.
There was a strong correlation between MTX AUC at week 1 and PASI at week 13 (rho = -0,08, p 0,0001).