An influence of selective pressure of antibiotics on gram-negatice bacterial flora resistance in the Haematology unit at the Teaching hospital Hradec Králové, Czech Republic
2005
Abstract
Aim of the study was to evaluate the relationship between usage of antimicrobial agents intended to treat infection caused by Gram-negative bacteria and resistance of those bacteria in the haemato-oncology unit at the University hospital. In the haemato-oncology setting a decrease of selective pressure of fluoroquinolones entailed a decrease of Enterobacter spp. strains resistant to fluoroquinolones.
In paradox, high resistance of Klebsiella pneumoniae strains to gentamicin was observed at the haemato-oncology wards with low consumption of gentamicin.