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An influence of selective pressure of antibiotics on gram-negatice bacterial flora resistance in the Haematology unit at the Teaching hospital Hradec Králové, Czech Republic

Publication at Faculty of Medicine in Hradec Králové |
2005

Abstract

Aim of the study was to evaluate the relationship between usage of antimicrobial agents intended to treat infection caused by Gram-negative bacteria and resistance of those bacteria in the haemato-oncology unit at the University hospital. In the haemato-oncology setting a decrease of selective pressure of fluoroquinolones entailed a decrease of Enterobacter spp. strains resistant to fluoroquinolones.

In paradox, high resistance of Klebsiella pneumoniae strains to gentamicin was observed at the haemato-oncology wards with low consumption of gentamicin.