Detection of carbapenemases in enterobacteria by MALDI-TOF mass spectrometry, inhibitor-based phenotypi tests, and molecular microbiology techniques

Abstract

Finding a reliable method for the detection of carbapenemases in enterobacteria and some Gram-negative non-fermenting rods is a big challenge for current clinical microbiological diagnosis. This article summarizes the possibilities for carbapenemase detection in enterobacteria provided by inhibitor-based phenotypic tests, MADLI-TOF mass spectrometry, and molecular microbiology techniques.

Keywords

• Enterobacteriaceae
• KPC
• MBL
• meropenem
• DDST