One-pot regioselective vinylation of tetrazoles: preparation of 5-substituted 2-vinyl-2H-tetrazoles

Abstract

The one-pot regioselective preparation of 5-aryl/alkyl-2-vinyl-2H-tetrazoles from 5-substituted tetrazoles via a very simple procedure using 1,2-dibromoethane and triethylamine without the need of any catalyst is described.

Keywords

• nitrogen heterocycles
• regioselectivity
• vinylation
• tetrazole