Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives

Abstract

A few series of 3,5-disubstituted furanones bearing an alkoxy-, aryloxy- and alkylidene groups at C(5) were prepared, and their antifungal and cytostatic activity evaluated.

Keywords

• antifungal activity
• cytostatic activity
• furanones
• butenolides
• synthesis
• Pd-catalysis
• flow cytometry